Dr Ron Rosedale -- Leptin -- Its Essential Role in Health, Disease, and Aging

T he Ob mouse is a strain of mouse that has a genetic mutation that makes it obese and unhealthy. It has been used for many years as a model of obesity to do research on,
though the reason that it was obese had eluded scientists. This changed when, in 1994, Jeffrey Friedman discovered that this mouse lacked a previously unknown hormone called leptin, and when it was injected with leptin it became thin, vibrant, and very healthy within weeks.

This made headlines around the world, "the cure for obesity found" and pharmaceutical companies started tripping over themselves with trillion dollar signs in their eyes to be the first to genetically manufacture leptin on a large-scale. This did not last long. When people were tested for leptin, it was found that, unlike the Ob mouse, they did not lack leptin; on the contrary almost all overweight and obese people have excess leptin. These people were "leptin resistant" and giving extra leptin did little good. The financial disappointment was extreme and scientists working for pharmaceutical companies said that leptin wasn't important anymore since they could not find a drug to control it, and therefore the industry couldn't make money on it.

Metabolic Syndrome - Five Indicators

D r Peter Attia in his YouTube Video talk on human health, explains there are 5 indicators for Metabolic Syndrome.

What are the 5 symptoms?
  1. Hight blood glucose
  2. High blood pressure
  3. Low HDL numbers
  4. High triglycerides
  5. Large waistline (more than 40 inch)
If you have any 3 of these 5 conditions, you have Metabolic Syndrome.

Watch the video and take Dr Attia's advice (after you talk to your own doctor, of course).

During the video Dr Attia explains, he had Metabolic Syndrome, but didn't realise until his wife suggested he did something about his growing waistline.

Crash Sends Bus Driver Through Windscreen

Crash Sends Bus Driver Through Windscreen

A little shaken, but unhurt. Funny.

What was the pickup driver doing?

There's a strong case for compulsory seatbelt use.

Dr Rosedale - Why Calcium Supplements Increase Heart Attacks

Why Calcium Supplements Increase Heart Attacks

Dr Rosedale explains why calcium supplements impair health, and why you should stop taking them.

Go Carnivore Go!

T oday, Monday 27th April, I started the 30-Day Meat Only Challenge. I've been eating low carb for a few years. High fat, adequate protein, and very low carbos. Normally, 50 grams a day or under. Some days it's zero carbs. I include dairy products, small amounts of salad vegetables and berries once or twice a month. I stopped eating 85-90% dark chocolate, as I had difficulty digesting it.

If I visit friends, I may have plain ice cream, but I won't eat bread, cakes, biscuits, chocolate or other treats. I don't eat grains, potatoes, starches, sugars, so-called vegetable oils (PUFA), or trans-fats. I stopped eating bread and rice a few years back, and never been a big potato eater. I quit eating factory / industrialised foods around the same time. I get energy mostly from mono and saturated fats.

Protein Intake And Body Odour

T oday I have B.O. and I know where its coming from. Protein. My dietary split is around 80% fat, 15-20% protein, 0-5% carbs. I eat a low carb diet.

Yesterday, I cut calories and ate leftovers, whatever was in the fridge. I added a lot of butter to the cook, but protein still hit a high number. You can see from the Fitday graphic protein was 27%, which is a little high. In the second Fitday graphic reflects what I try to keep protein at 20% or under.

Excess protein in the diet is excreted in urine and in sweat. That acrid, musky smell you have is the excess protien pushed out the body in the form of urea and ammonia.

If you're on a high fat or high carb diet, you won't suffer. If you increase protein above what the body needs or can use. We have no protein stores in the body. If the body cannot use excess protein, it must get rid of it. Result? That awful smell.

I heard people say to shower and you'll get rid of the smell. It won't. The body will keep excreting excess, even if you shower.

Cut protein consumption to remove that awful smell.

Dr Rosedale - Boston Speech At The Heinz Conference

Dr Rosedale - Boston Speech at the Heinz Conference

My favourite doc, giving a talk on health

Dr Rosedale - Leptin And Your Health

Leptin And Your Health

Dr Rosedale explains leptin and how it affects you.

Dr Rosedale - Exposing The Cholesterol Myth

Cholesterol Is Not The Major Culprit In Heart Disease

Dr Rosedale Exposing the fraud on fats.

Explains why we got it wrong.

Feedlots. Carbs. Fat.

What is a feedlot?

It's a feeding operation used in intensive animal farming for finishing livestock prior to sale or slaughter.

What is their function?

As the name suggests, to feed and fatten livestock for market. Cattle spend most of their life grazing range-land or immature grain fields. When cattle reach a weight of 650 to 700 pounds (300 kg), they are transferred to a feedlot.

An animal can gain an additional 400 pounds (180 kg) during its 200 days in the feedlot. An impressive 60% weight gain.

Carbs Are Not An Essential Nutrient

Today, you will require ZERO carbohydrates in your diet to stay alive. Are you sure?

Yes. Lets clarify.

The absolute essential nutrients for human health and survival, are:

* Amino acids          * Minerals
* Fatty acids            * Water
* Electrolytes           * Energy
* Vitamins

It is the last – energy – which generates the most controversy and conflict in nutrition. Most of which is largely defined, not by science, but by other agendas; political, ideological, and complete nonsense.

The controversy ends when you look at the science. Any biology or medical biochemistry literature will confirm:

"The human body has no dietary requirement for carbohydrates".

You’ll be reassured to know that you don’t have to eat carbohydrates to live. It’s not an essential nutrient. One of the first things learnt in nutrition is:

"What does the body NOT make, that you MUST eat."

You won’t find carbohydrate on the list.

For the complete post, go to: http://highsteaks.com/carbohydrates/

Dogs Are Carnivores

Some Vets Don't Understand this?

Y eah, its true. Some vets don't get it that dogs are carnivores, descended from the Gray Wolf (Canis Lupus). Some vets are so conditioned they cannot think outside the milieu. They unquestioningly believe all they are told.

I watched a video talk by Professor Seyfried on cancer. In the talk he relayed a story of a lady who cured her dogs cancer tumour, by taking her dog off manufacturers dog food and feeding it raw meat. The vet was surprised the dog lived and phoned Professor Seyfried to get more info. The vet retorted he could not give dogs raw meat.

There appears to be some doubt whether dogs are carnivores or omnivores. Go take a look at rawfed.com website, where any doubt about a dogs ancestry and dietary habits are covered in detail and with great clarity. Including links to supporting evidence from those in the know.

Paleo Diet & Strength Training Biochemistry

Doug McGuff M.D.

D oug McGuff's talk on High Intensity Training and its benefits. He covers some biochem, explaining the body's response to strength training, health and fitness.

McGuff also talks on his book, Body By Science, genetics, diet, obesity, nutrition, muscle growth, over-training, fatigue, ageing, and the body's stress during training.

Cardio Does Not Exist

Doug McGuff M.D.

D oug McGuff at the 21 Convention 2010, explains why cardio as generally perceived, does not exist. The heart / lungs / vascular system are not exclusively tied to the aerobic system, in the mitochondria.

Watch the short video (5 minutes), for an explanation and overview.

In Search Of The Perfect Human Diet

In Search Of The Perfect Human Diet

D ocumentary by C.J. Hunt to find the perfect diet for humans to eat. With so many conflicting views and different diet gurus, which is the best diet for optimal health?

Hunt travels the world in search of the answer.

What Medical Doctors Are Taught About Nutrition In Med School And Beyond - Dr Jason Fung

Y ou go to your doctor expecting him/her to understand your dietary problems and to have some insight.

Most have little knowledge of diet and nutrition, unless they specialise. See what Dr Jason Fung has to say. It's a short video, running 70 seconds in length.

Peter Attia - An Advantaged Metabolic State

Human Performance, Resilience & Health

E xcellent talk on metabolism, exercise, performance while in ketosis.

Minimal glucose usage during heavy exercise. Fully explained in this talk.

Sports Nutrtion with Dr. Peter Attia - Protein

Dr. Peter Attia's views on protein requirements for athletes

P rotein use for athletes ranges from:

1g per kg of lean body weight at the low end
2g per kg of lean body weight at the high end

As a swimmer he consumes around 1.5g per kg of lean body weight.

Dr Peter Attia MD Video - AHS12

The Straight Dope on Cholesterol

E verything you wanted to know about Cholesterol, but were afraid to ask!

Forget the half-truths and misinformation. Watch the video and get the facts.

Dr. Peter Attia: Readdressing Dietary Guidelines

Dr. Peter Attia: Readdressing Dietary Guidelines

D r Attia questions the validity of current dietary recommendations, by walking through the history and evolution of Low-fat / High-carb dogma. He dismantles and finally puts to bed the erroneous Lipid Hypothesis. He shows how studies used to support the theory were flawed, the research incomplete, wrongly interpreted, including the suppression of contradictory studies and results.

That's not how true science works.

The research should have focused on High-Triglycerides and Low-HDL in the blood, which are accurate predictors of Metabolic Syndrome.

They got it wrong.

Dr Peter Attia - The Ketogenic Diet

Very Low Carb Performance

D r Peter Attia talks about his experience on the Ketogenic Diet and the amazing changes he experienced, from physical endurance to mental acuity.

As a fitness fanatic who has undertaken a 24 hour fast and a bike ride for 6 hours while still fasting. Done while on a Ketogenic very low carb diet.

In the talk he explains why its important to keep protein levels low. High enough to meet the body's needs, but not so high that excess is turned into blood glucose via gluconeogenesis.

At 8:23 Dr Attia reveals he was eating around 240 grams of protein a day. That's too much. Why? The body will convert excess protein to glucose, taking the body out of ketosis and in effect killing the benefits of the Ketogenic diet.

How Bad Science and Big Business Created the Obesity Epidemic

D avid Diamond, Ph.D., of the University of South Florida College of Arts and Sciences shares his story about obesity. He tells how he lost weight and reduced his triglycerides by eating red meat, eggs and butter.

At 16:00 minutes into the video he explians how sugar and carbs consumption caused cholesterol / triglycerides to rise in the blood.

At 61:00 minutes he shows how sugar causes heart disease.

When sugar and carbs were eliminated / reduced, caused a corresponding drop in triglycerides in the blood.

Spend an hour of your time to learn about the lies propagated by corporations and pharma industry to sell, sugar, carbs, cholesterol and drugs.

Researched and honestly told by a neuroscientist, who has no vested interest and no axe to grind.

Essential viewing.

Thomas Seyfried's Talk On Cancer

A Metabolic Disease With Metabolic Solutions

T he whole talk is excellent, there's no doubting it, but some points of the talk are so good, I had to highlight them. I selected a few.

Link to the video on YouTube.

At 23:15 - Biomarkers of Calorie Restriction

1. Reduced Blood Glucose

2. Elevated Ketone Bodies
 - B-Hydroxybutyrate
 - Acetoacetate
 - Acetone

These are water soluble breakdown products of fat, and they are powerful energy metabolites that will allow our body to function at maximal energy efficiency. But only when the glucose goes down.


"You don't get cancer unless you damage your mitochondria"

I f you have cancer or if you know someone who has cancer, watch this video. Do them a favour and get them to watch it.

Essential viewing, particularly for low-carb sceptics.

The Secrets of Sugar - Documentary

The Fifth Estate - CBC News

I f you had lingering doubts about sugar consumption, this documentary by the Canadian Broadcasting Corporation, may go some way to eliminating them.

The documentary looks at sugar content in manufactured foods, sugar consumption by the average family, its affects on weight and health, and the dirty tricks played by the sugar industry.

There's an interview with Professor Lewis Cantley, of Weill Cornell Medical College, a leading authority on cancer. In the interview, he admits to removing sugar from his diet.

Eating Carbs, Ageing And Lifespan

Carbs. Aging. Longevity.

W ith old age comes the associated problems of ageing, cancer, diabetes, arthritis, alzheimers, memory loss, parkinsons, osteoporosis, sarcopenia and other diseases.

Scientists have known for a long time how to extend lifespan. To make laboratory animals live longer, healthier lives, you reduce their calories by 30-40%. Unfortunately it's not a practical solution for most humans, as you constantly feel hungry, cold, and tired.

Cynthia Kenyon is a U.S. geneticist and Professor for the Biology of Aging at the University of California, San Fransisco. She began her work by questioning: Why do squirrels live 25 years, but rats only live 2 years? She wondered if genes played a part in ageing.

Oils And Fats To Eat

Low-To-No-Carb Diet!

S witching to a low-carb diet appears a daunting prospect, but its quite simple. The hard part is overcoming your old habits and inertia. Breaking your eating habits and forming new ones, is the difficult part.

There's also the battle to get the truth. Overcoming propaganda and conditioning from years of wrong information and marketing hype.

The government indifference and the health industry's total disinterest in your good health. Healthy, happy humans are no-good to the pharmaceutical industry, they want sick people, to sell their ineffective drugs.

The giant food corporations know carbs are addictive. Its in their interest to feed people carbs, to keep them coming back for more. Its hard breaking the carb habit.

Once you switch to low-carb, it amazing the health difference.

BBC Bitesize Science Info Is Wrong

The BBC Bitsize website, designed specifically for helping children learn and revise, provides incorrect and misleading information.

A balanced diet contains the different nutrients in the correct amounts to keep us healthy. Certain foods are not necessarily 'bad' for us, but eating too much of them could be. We will look at what food types are needed, how they are digested.
The page on nutrition lists:

There are seven different nutrients:
- carbohydrates                     - minerals
- proteins                                - fibre
- fats                                        - water
- vitamins

Are Carbohydrates Essential?

D espite oft-heard claims to the contrary, there is no physiological requirement for dietary carbohydrate. Even the RDA handbook acknowledges this, right before recommending that a prudent diet should contain a lot of carbohydrates. To understand why carbs aren’t essential, I need to discuss the concept of an essential nutrient briefly.

An essential nutrient is defined as:
  • Any nutrient that is required for survival
  • Can’t be made by the body
Quoting from my own Rapid Fat Loss Handbook:
The second criterion is the reason that dietary carbohydrate is not an essential nutrient: the body is able to make as much glucose as the brain and the few other tissues need on a day-to-day basis from other sources. I should mention that the body is not able to provide sufficient carbohydrate to fuel high intensity exercise such as sprinting or weight training and carbs might be considered essential for individuals who want to do that type of exercise. I’ll come back to exercise later in this article.
From the standpoint of survival, the minimum amount of carbohydrates that are required in a diet is zero grams per day. 

The body can make what little it needs from other sources.

Excerpt from: How Many Carbohydrates Do You Need? - Lyle McDonald

How Many Carbs Do You Need?

No Such Thing As Essential Carbs

H ow many carbohydrates are required in the human diet?


Dr Eric C. Westman, M.D. who practices and teaches at Duke University, N.C. explains the bodies requirement for carbohydrates.

There are no dietary requirements for carbohydrates. The body can produce what little blood sugar it needs from other dietary sources.

Macronutrient Ratios

The 80 / 20 rule

W hat percent of protein or fats to eat in my diet?

The 80 / 20 rule.

(aka Pareto Principle).

Eat 80% fats / 20% protein.

A little more detail.

Eat animal fats. Saturated fats. Butter, ghee, lard, suet, tallow. These make up most calories.

Eat cheese with zero (or close to zero) carbs. The closer to milk form, the higher the carb content, and lactose.

Current H.I.T. Exercise Routine

For a while I did the StrongLifts 5x5, but after 6 weeks, realized it wasn't for me. Going to the gym 3x times a week was way too much, and left little time for skating, once you factor in work and travel time.

I switched back to H.I.T, and followed Doug McGuff's Big 5 training routine, as detailed in his book, Body By Science. I've done H.I.T. before, and the StrongLifts 5x5 didn't feel quite right. I prefer using machines, and the heavy trashing of muscles you get with High Intensity Training. The intense burn of lactic acid. Sickening, painful, but good.

Skating is my primary sport, but I enjoy the weekly H.I.T. session, and the rubber legs walking home, after the workout.

Georgia Ede M.D. Video - AHS 2012

The Risks and Benefits of Eating Plants

We tend to think of plants as harmless helpless immobile organisms, at the mercy of heartless herbivores, insects, birds, rodents and other life forms, that consume them without respite. The truth is some way off from that cute view.

Georgia Ede, M.D. gives a talk on the undesirable consequences of eating plantfoods, including fruits, vegetables, nuts and seeds. These often contain toxins, anti-nutrients, lectins, and  poisons.

Google Keep Character Limit

G oogle Keep is a nice little todo list, reminder, note-taker. I use it frequently, mostly for short notes or reminders on my phone. I recently copied and dumped a lot of text into Keep, which took it, but truncated about a third.

Keep maximum characters per note is: 9914

Dr. Ron Rosedale's Talk - AHS 2012 Transcipt

The Deeper Roots of Health and Diet as Told by Our Ancestors

I felt the talk was of such importance, I took the time to transcribe it. Reading through it, many things become clear, I didnt get watching the video.

Video available on YouTube.

Thank you for coming. Just by way of a very brief introduction, in the low-carb circles I'm kinda last man, last original man standing. There were several people espousing a low carb diet twenty years ago, I'm one of them. Most were correlating it with a high protein diet and I'm glad to see that I have convinced people that's not the case, And that shouldn't be the case. I was also the first person to connect leptin to diet and health and then mTOR. I fought against cholesterol being a villain for twenty years.

Alleged Benefits Of Eating Bananas

List Of Alleged Benefits

In view of the problems I experience eating this fruit, I have to question some of the so called benefits, and whether they apply to me? (or others who experience similar problems).

1. Not applicable
2. Not applicable
3. Not applicable
4. Not applicable
5. Not applicable
6. Not applicable
7. Not applicable
8. Not applicable
9. I'm on high-fat diet, so probably not.
10. Not applicable

Probably designed and produced by the banana marketing board! As with most marketing. Its bullshit.

Mike Mentzer HIT Training - Marcus Reinhardt

HIT Workout 3-Day Split

4 seconds up.
2 second pause.
4 seconds down
1 min 20 secs per exercise

Rep Range / Set Range
Aim for 6 / 8 reps each set
A single set worked to failure

Supersets / Pre-exhaust
Start with few reps of second exercise as a warm up
Use second exercise to pre-exhaust muscles

Warm up
3 or 4 reps with lighter weights to warm muscle and increase blood flow

Mike Mentzer HIT Training Video

Mike Mentzer HIT Training

Putting Markus Reinhardt through the paces.

Workout carried over a punishing three days.

Michael Pollan: The Omnivore's Dilemma

E ntertaining and educational talk on the food we eat and the impact it has on our lives, our health and the environment.

I laughed when he explained they tested McDonalds fries and found them to be 50% corn! They're potatoes. How can that be?

Based on his book of the same name.

Warped And Totally Insane

W atch the video of the CD Shattering at 170,000FPS!

They spin several CDs to destruction and record at different frame rates.  Its weird how the CDs warp and flutter, moments before they shatter.

Brought to you by: The Slow-Mo-Guys

How much protein do I need every day?

W hen I researched dietary protein intake on the Net, including weight training forums, I saw wildly speculative quantities to consume, ranging from 150g to 350g a day.

I reckon none of the numbers were science based, other than broscience. You could probably get away with consuming 350g of protein if you're on high-carbs, which I'm not. I get energy from fats, and have no desire to switch to burning sugar.

As we cannot store protein, excess protein turns to sugar, or gets dumped out the body as urea. Our bodies efficiently recycle amino acids, to minimise protein usage. Our dietary protein requirements are quite low, and most people are clueless on how much is needed.

I did a previous post about Dr Rosedale's views on daily protein requirements.

How To Chop An Onion

Fast, easy way to chop an onion.

Watch and learn.

Dr Rosedale's Talk On Protein - Good, Bad And Ugly

Dr Rosedale gave a talk on the effects of excess protein, and how it can adversely impact on health.

Even eating a low-carb diet, there are dangers associated with high levels of protein consumption. Its common for people to cut carbs and increase protein, to make up the calories. Not a good idea. Increasing fat intake is the answer.

The talk was given in 2006 to a American Medics. It's available on Dr Rosedale's website along with a complete transcript of the talk.

Protein - The Good, The Bad, The Ugly.

Read or listen. Talk runs approx 40 minutes.

Dr Rosedale Explains Protein On His Low-Carb Diet

Protein is the only portion of the Rosedale diet you must track, for a very good reason. You don't need to pour over each gram, but everyone has an optimal protein intake most conducive to health. It's important to stay within that range.

Each day, eat one gram of protein for every kilo of lean body mass (your body weight minus all body fat). The easiest way to calculate your recommended protein intake is to imagine your ideal body weight in kilograms and consume roughly one gram per kilo. Split the protein intake between your meals. Assuming three meals, you would eat 20g protein in each meal.


A male weighing 150lbs, would be approx 120lbs - 130lbs lean body mass. Converted to kilos its 55kg - 60kg. This is the daily recommended protein intake, in grams. Add 5 grams if you exercise or unusually muscular.

A female weighing 150lbs, would be approx 110lbs - 120lbs lean body mass. Converted to kilos its 50kg - 55kg. This is the daily recommendation of protein, in grams. Add 5 grams if you exercise or unusually muscular.

According to this calculation, my approximate protein requirements are:

50 grams - non-active days (days off)

60 grams - active days (skating / training)

Source: Dr Rosedale Health Plan - Protein

Dr Ron Rosedale Explains Eating Saturated Fats

F irst of all, when I say that I want you to eat fat, the "you" is your cells. I want your cells to eat fat. If you have excess body fat, especially visceral fat, we want your cells to eat it. If they are allowed to eat your stored fat, you need not put so much fat in your mouth, but "you" are still eating a high-fat diet. Once again, whether or not you are allowed to eat your stored fat depends on significant metabolic
hormones, mainly proper leptin function. "I want you to burn fat as fuel as opposed to glucose, whether it comes from immediate dietary intake or whether it comes from oxidation of stored fats." Maintaining proper insulin and leptin activity will allow you to burn fat. "Thus it is imperative that non-fiber carbohydrates be kept to a minimum." When you are burning stored fat you are eating and hunger will be minimized.

Dr. Ron Rosedale's Video - AHS 2012

The Deeper Roots of Health and Diet

Excellent presentation that explains why we have glucose, its evolutionary history, why its used, why we don't need it as a fuel, and why fat is a better energy source.

Dr Rosedale also explains the consequences of consuming carbohydrates and their impact on health.


This important talk contained some essential information. I transcribed it, to allow perusal of the text to take in facts missed watching the video.